The objectives to this procurement are: With approvals from relevant Contractor's internal review committees, and with informed consent from donors or their next-of-kin -- to collect human tissues, cells, and fluids (i.e. lung, liver, bronchus, colon, pancreas, blood urine, pleural effusions) at the time of surgery and at autopsy from patients with medical and personal histories (epidemiological profiles), also available by informed consent. Autopsies will be both immediate (2 hrs) and intermediate (12 hrs.) and specimens are to be delivered within 2 hours of availability from the pathologist, at any time of day or night, while patient profiles (stored with coded references to protect the identify of the donors) will be """"""""securely"""""""" stored in the contractor's facility until delivered to the NIH at the request of LHC. In addition, selected specimens will be examined (""""""""characterized"""""""") for histopathological condition by light and EM microscopy, in vitro viability and the detection of various cellular components such as hormones and oncogenes by histochemistry, including immunological methods.

Agency
National Institute of Health (NIH)
Institute
Division of Cancer Epidemiology And Genetics (NCI)
Type
Research and Development Contracts (N01)
Project #
N01CP095624-004
Application #
3635103
Study Section
Project Start
1989-03-31
Project End
1993-03-30
Budget Start
1992-09-15
Budget End
1993-03-30
Support Year
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201