Abstract

The overall mission of this core facility is to provide the necessary equipment and technical suppport for tissue culture and baculovirus services to allow rigorous pursuit of the goals of the Program project. The rationale is to establish these services in a central location (third floor, Vollum Institute) to be shared by members of the four research groups, in order to further scientific exchange between the participating laboratories and to eliminate duplication in costs of equipment, supplies and salaries. Establishment of this core facility will therefore save a substantial amount of research effort and costs for each of the component laboratories. The core facility will provide several services critical for the development of each project.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Program Projects (P01)
Project #
5P01DK044239-09
Application #
6301122
Study Section
Project Start
2000-04-01
Project End
2001-03-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
9
Fiscal Year
2000
Total Cost
$194,671
Indirect Cost

  Institution

Name
Oregon Health and Science University
Department
Type
DUNS #
009584210
City
Portland
State
OR
Country
United States
Zip Code
97239

  Publications

Zhang, Qinghong; Wang, Su-Yan; Fleuriel, Capucine et al. (2007) Metabolic regulation of SIRT1 transcription via a HIC1:CtBP corepressor complex. Proc Natl Acad Sci U S A 104:829-33
Soderling, Scott H; Guire, Eric S; Kaech, Stefanie et al. (2007) A WAVE-1 and WRP signaling complex regulates spine density, synaptic plasticity, and memory. J Neurosci 27:355-65
Felmy, Felix (2007) Modulation of cargo release from dense core granules by size and actin network. Traffic 8:983-97
Zhang, Qinghong; Wang, Su-Yan; Nottke, Amanda C et al. (2006) Redox sensor CtBP mediates hypoxia-induced tumor cell migration. Proc Natl Acad Sci U S A 103:9029-33
Dodge-Kafka, Kimberly L; Langeberg, Lorene; Scott, John D (2006) Compartmentation of cyclic nucleotide signaling in the heart: the role of A-kinase anchoring proteins. Circ Res 98:993-1001
Wan, Lei; Almers, Wolfhard; Chen, Wenbiao (2005) Two ribeye genes in teleosts: the role of Ribeye in ribbon formation and bipolar cell development. J Neurosci 25:941-9
Pawson, Tony; Scott, John D (2005) Protein phosphorylation in signaling--50 years and counting. Trends Biochem Sci 30:286-90
Zhang, Qinghong; Nottke, Amanda; Goodman, Richard H (2005) Homeodomain-interacting protein kinase-2 mediates CtBP phosphorylation and degradation in UV-triggered apoptosis. Proc Natl Acad Sci U S A 102:2802-7
Taraska, Justin W; Almers, Wolfhard (2004) Bilayers merge even when exocytosis is transient. Proc Natl Acad Sci U S A 101:8780-5
Wayman, Gary A; Kaech, Stefanie; Grant, Wilmon F et al. (2004) Regulation of axonal extension and growth cone motility by calmodulin-dependent protein kinase I. J Neurosci 24:3786-94

Showing the most recent 10 out of 65 publications