The overall goals of Community Engagement (CE) are to deliver the technologies developed within the Resource to the broader scientific community, and to enlist the community in defining the direction of development efforts. Community engagement will include the dissemination of technologies and methodologies developed by the resource to the bioNMR and biomedical communities. This includes delivery of the Virtual Machines for download, access to the cloud computing resources, access to data models, software and source code developed by the resource, as well documentation of the overall approach to building the resource technologies. Community engagement will also include extensive, hands-on training for the biomolecular NMR user community, through workshops (both internal and external), interactive tutorials, and access to support staff for assistance. An overarching goal is to make the resource sustainable by the bioNMR community as a whole. To accomplish this goal, the community will be engaged to become active participants in the governance and future development of the NMRbox resource. Efforts for this level of engagement include online, community code repositories (such as GitHub), establishing additional NMRbox instances across the globe, and plans to commercialize the core kernel of the technology so it can be self-sustaining in the future. One facet is the concrete delivery of the technologies and methodologies developed as part of the resource to the bio-NMR and related communities. This is covered in the Technology Dissemination portion of CE. A second facet is delivery of training to the user communities on how to use the Center?s resources for cutting edge applications in biomedical research. This is covered in the Technology Training portion of CE. Enlistment involves interactive collaboration and service activities with external researchers, using active participation of the collaborator to impact and guide technology development. This encompasses projects smaller in scope than a DBP, frequently served by deploying existing technology in novel ways but in some cases involving modest adaptations of existing technology, to serve the needs of a specific investigator or application. These interactions encompass projects formerly described as Collaboration and Service, which now permeate the TRDs as well as CE. The fourth facet is the eventual migration of Resource technologies out of the Center and into the hands of the bio-NMR community. This is covered in the Sustainability of Technologies portion of CE.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Biotechnology Resource Grants (P41)
Project #
Application #
Study Section
Special Emphasis Panel (ZRG1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Connecticut
United States
Zip Code
Dashti, Hesam; Wedell, Jonathan R; Westler, William M et al. (2018) Applications of Parametrized NMR Spin Systems of Small Molecules. Anal Chem 90:10646-10649
Pupier, Marion; Nuzillard, Jean-Marc; Wist, Julien et al. (2018) NMReDATA, a standard to report the NMR assignment and parameters of organic compounds. Magn Reson Chem 56:703-715
Gryk, Michael R; Ludäscher, Bertram (2018) Semantic Mediation to Improve Reproducibility for Biomolecular NMR Analysis. Transform Digit Worlds (2018) 10766:620-625
Maciejewski, Mark W; Schuyler, Adam D; Hoch, Jeffrey C (2018) Practical Nonuniform Sampling and Non-Fourier Spectral Reconstruction for Multidimensional NMR. Methods Mol Biol 1688:341-352
Zambrello, Matthew A; Schuyler, Adam D; Maciejewski, Mark W et al. (2018) Nonuniform sampling in multidimensional NMR for improving spectral sensitivity. Methods 138-139:62-68
Markley, John L; Brüschweiler, Rafael; Edison, Arthur S et al. (2017) The future of NMR-based metabolomics. Curr Opin Biotechnol 43:34-40
Maciejewski, Mark W; Schuyler, Adam D; Gryk, Michael R et al. (2017) NMRbox: A Resource for Biomolecular NMR Computation. Biophys J 112:1529-1534
Delaglio, Frank; Walker, Gregory S; Farley, Kathleen A et al. (2017) Non-Uniform Sampling for All: More NMR Spectral Quality, Less Measurement Time. Am Pharm Rev 20:
Dashti, Hesam; Westler, William M; Markley, John L et al. (2017) Unique identifiers for small molecules enable rigorous labeling of their atoms. Sci Data 4:170073
Nguyen, Khiem; Puthenveetil, Robbins; Vinogradova, Olga (2017) Investigation of the adaptor protein PLIC-2 in multiple pathways. Biochem Biophys Rep 9:341-348

Showing the most recent 10 out of 22 publications