During the last three years, this project has: (1) conducted a series of multi-center studies evaluating pain and its treatment, both with non-minority and minority cancer patients, and determined risk factors for those patients indexed as having poor pain management, (2) developed a sequence of clinical trials of interventions to change both health care professional and patient behavior regarding pain and its management, based on a model of analgesic practice change, (3) refined our understanding of pain assessment measures and the relationship between pain severity and the impact of pain on the patient, especially the relationship between culture and language on pain report, and (4) demonstrated the utility of collaborative international studies of pain and pain treatment for assessing and treating U.S. cancer patients and for understanding factors that lead to poor pain management. The research goals of this funding period will focus on methods to reduce the number of patients who continue to receive inadequate pain control. These studies will: (1) implement both descriptive and intervention studies in multi-center studies performed in NCI-sponsored collaborative groups, (2) continue international studies of cancer pain, its assessment and its treatment and test methods of modifying health care practice of cancer pain management, and (3) incorporate medical decision making methodology to establish new ways of evaluating the effectiveness of pain and symptom control therapies. The studies described will make use of established collaborations with international pain and oncologic investigators, and the Eastern Cooperative Oncology Group, and develop new collaborations with the UTMD Anderson NCI-funded research base and the Radiation Treatment Oncology Group.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
2R01CA026582-17A1
Application #
2612741
Study Section
Special Emphasis Panel (ZRG2-SSP (03))
Program Officer
Varricchio, Claudia G
Project Start
1986-07-01
Project End
2002-01-31
Budget Start
1998-04-01
Budget End
1999-01-31
Support Year
17
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Neurology
Type
Other Domestic Higher Education
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030
Hansen, Chase C; Smith, Joshua B; Mohamed, Abdallah S R et al. (2017) Cognitive function and patient-reported memory problems after radiotherapy for cancers at the skull base: A cross-sectional survivorship study using the Telephone Interview for Cognitive Status and the MD Anderson Symptom Inventory-Head and Neck Module. Head Neck 39:2048-2056
Wang, Xin Shelley; Shi, Qiuling; Dougherty, Patrick M et al. (2016) Prechemotherapy Touch Sensation Deficits Predict Oxaliplatin-Induced Neuropathy in Patients with Colorectal Cancer. Oncology 90:127-35
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Wang, Xin Shelley; Shi, Qiuling; Williams, Loretta A et al. (2016) Prospective Study of Patient-Reported Symptom Burden in Patients With Non-Small-Cell Lung Cancer Undergoing Proton or Photon Chemoradiation Therapy. J Pain Symptom Manage 51:832-8
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Jones, Desiree; Vichaya, Elisabeth G; Cleeland, Charles S et al. (2014) Screening for depressed mood in patients with cancer using the MD Anderson Symptom Inventory: investigation of a practical approach for the oncologist. J Oncol Pract 10:e95-102
Wang, Xin Shelley; Zhao, Fengmin; Fisch, Michael J et al. (2014) Prevalence and characteristics of moderate to severe fatigue: a multicenter study in cancer patients and survivors. Cancer 120:425-32

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