Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA053783-03S1
Application #
2095483
Study Section
Medical Biochemistry Study Section (MEDB)
Project Start
1991-02-01
Project End
1994-01-31
Budget Start
1993-02-01
Budget End
1994-01-31
Support Year
3
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Indiana University Bloomington
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
006046700
City
Bloomington
State
IN
Country
United States
Zip Code
47401
Townsend, Danyelle M; Findlay, Victoria J; Fazilev, Farit et al. (2006) A glutathione S-transferase pi-activated prodrug causes kinase activation concurrent with S-glutathionylation of proteins. Mol Pharmacol 69:501-8
McIlwain, C C; Townsend, D M; Tew, K D (2006) Glutathione S-transferase polymorphisms: cancer incidence and therapy. Oncogene 25:1639-48
Klein, S B; Yeivin, A; Becker, G et al. (1994) IDO mutants cross resistant to type I interferon retain p91-dependent gene induction. J Interferon Res 14:333-41
Ozes, O N; Taylor, M W (1994) Reversal of interferon-gamma-resistant phenotype by poly(I:C): possible involvement of ISGF2 (IRF1) in interferon-gamma-mediated induction of the IDO gene. J Interferon Res 14:25-32
Reiter, Z; Taylor, M W (1993) Interleukin 2 protects hairy leukemic cells from lymphokine-activated killer cell-mediated cytotoxicity. Cancer Res 53:3555-60
Ozes, O N; Taylor, M W (1993) Reversal of an interferon-gamma-resistant phenotype by poly(I:C): possible role of double-stranded RNA-activated kinase in interferon-gamma signaling. J Interferon Res 13:283-8
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Burkin, D J; Kimbro, K S; Barr, B L et al. (1993) Localization of the human indoleamine 2,3-dioxygenase (IDO) gene to the pericentromeric region of human chromosome 8. Genomics 17:262-3
Reiter, Z; Ozes, O N; Blatt, L M et al. (1992) Cytokine and natural killing regulation of growth of a hairy cell leukemia-like cell line: the role of interferon-alpha and interleukin-2. J Immunother (1991) 11:40-9
Reiter, Z; Ozes, O N; Blatt, L M et al. (1992) A dual anti-tumor effect of a combination of interferon-alpha or interleukin-2 and 5-fluorouracil on natural killer (NK) cell-mediated cytotoxicity. Clin Immunol Immunopathol 62:103-11

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