Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA007912-03
Application #
2120344
Study Section
Drug Abuse Biomedical Research Review Committee (DABR)
Program Officer
Thadani, Pushpa
Project Start
1993-12-15
Project End
1997-11-30
Budget Start
1995-12-05
Budget End
1997-11-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Oregon Health and Science University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
009584210
City
Portland
State
OR
Country
United States
Zip Code
97239

  Publications

Wallisch, Michael; Subban, Chinmayee V; Nettleton, Rosemary T et al. (2010) Chronic in utero buprenorphine exposure causes prolonged respiratory effects in the guinea pig neonate. Neurotoxicol Teratol 32:398-405
Silverman, Daniel A N; Nettleton, Rosemary T; Spencer, Katherine B et al. (2009) S-Methadone augments R-methadone induced respiratory depression in the neonatal guinea pig. Respir Physiol Neurobiol 169:252-61
Nettleton, Rosemary T; Wallisch, Michael; Olsen, George D (2008) Respiratory effects of chronic in utero methadone or morphine exposure in the neonatal guinea pig. Neurotoxicol Teratol 30:448-54
Wallisch, Michael; Nelson, Cole S; Mulvaney, Julia M et al. (2007) Effects of chronic opioid exposure on guinea pig mu opioid receptor in Chinese hamster ovary cells: comparison with human and rat receptor. Biochem Pharmacol 73:1818-28
Smith, Sue Ann; Stupfel, James T; Ilias, Nasreen A et al. (2004) Guinea pig mu opioid receptor: brainstem expression in the morphine-exposed neonate. Neurotoxicol Teratol 26:121-9
Matsuda, A Y; Olsen, G D (2001) Chronic in utero morphine exposure alters mu-agonist-stimulated [35S]-GTPgammaS binding in neonatal and juvenile guinea pig brainstem regions associated with breathing control. Neurotoxicol Teratol 23:413-9
Gray, R E; Munks, M W; Haynes, R R et al. (2001) Mu opioid receptor efficacy and potency of morphine-6-glucuronide in neonatal guinea pig brainstem membranes: comparison with transfected CHO cells. Brain Res Bull 54:499-505
Hunter, M A; Vangelisti, G R; Olsen, G D (1997) Chronic intermittent in utero exposure to morphine: effects on respiratory control in the neonatal guinea pig. Biol Neonate 72:293-304
Olsen, G D; Murphey, L J (1995) Effects of morphine and cocaine on breathing control in neonatal animals: a minireview. NIDA Res Monogr 158:22-39
Murphey, L J; Olsen, G D (1995) Developmental change of mu opioid receptors in neonatal guinea pig brain stem. Brain Res Dev Brain Res 85:146-8

Showing the most recent 10 out of 11 publications