Orphan Receptors of the Peroxisome Proliferator Family

Noonan, Daniel J.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 5R01DK047132-04
• Application #: 2146465
• Study Section: Biochemical Endocrinology Study Section (BCE)
• Project Start: 1993-02-01
• Project End: 1997-01-31
• Budget Start: 1996-02-15
• Budget End: 1997-01-31
• Support Year: 4
• Fiscal Year: 1996

Institution

• Name: University of Kentucky
• Department: Biochemistry
• Type: Schools of Medicine
• DUNS #: 832127323
• City: Lexington
• State: KY
• Country: United States
• Zip Code: 40506

Publications

Intrasuksri, U; Rangwala, S M; O'Brien, M et al. (1998) Mechanisms of peroxisome proliferation by perfluorooctanoic acid and endogenous fatty acids. Gen Pharmacol 31:187-97

Rangwala, S M; O'Brien, M L; Tortorella, V et al. (1997) Stereoselective effects of chiral clofibric acid analogs on rat peroxisome proliferator-activated receptor alpha (rPPAR alpha) activation and peroxisomal fatty acid beta-oxidation. Chirality 9:37-47

Noonan, D J; O'Brien, M L (1997) A hypothetical mechanism for fat-induced rodent hepatocarcinogenesis. Adv Exp Med Biol 422:127-35

O'Brien, M L; Rangwala, S M; Henry, K W et al. (1996) Convergence of three steroid receptor pathways in the mediation of nongenotoxic hepatocarcinogenesis. Carcinogenesis 17:185-90

Henry, K; O'Brien, M L; Clevenger, W et al. (1995) Peroxisome proliferator-activated receptor response specificities as defined in yeast and mammalian cell transcription assays. Toxicol Appl Pharmacol 132:317-24

Mukherjee, R; Jow, L; Noonan, D et al. (1994) Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators. J Steroid Biochem Mol Biol 51:157-66