The diagnostic capabilities of a new confocal laser scanning ophthalmoscope/biomicroscope will be studied. The instrument overcomes most of the problems encountered in earlier approaches to quantitative diagnostics of the human eye and especially provides a considerable improvement in lateral as well as depth resolution of the different compartments of the human eye. It will image and evaluate the three-dimensional microscopic retinal anatomy, lens structure and anatomy, and the corneal topography. Details of all the cells of the cornea can be obtained because of its section-wise imaging capabilities. The confocal laser scanning approach has proven to be particularly valuable in epifluorescence cell studies. A powerful multi-microprocessor image processing system allows for real time reconstruction of three dimensional imaging data. The instrument promises new advantages for early quantitative diagnosis of glaucoma, cataract, and the normal and diseased cornes.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY006006-02
Application #
3261908
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1986-07-01
Project End
1990-09-29
Budget Start
1987-07-01
Budget End
1990-09-29
Support Year
2
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093