Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
2R01EY009224-04
Application #
2162857
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1993-05-01
Project End
2000-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Cedars-Sinai Medical Center
Department
Type
DUNS #
075307785
City
Los Angeles
State
CA
Country
United States
Zip Code
90048
Ghiasi, Homayon; Osorio, Yanira; Perng, Guey-Chuen et al. (2002) Overexpression of interleukin-2 by a recombinant herpes simplex virus type 1 attenuates pathogenicity and enhances antiviral immunity. J Virol 76:9069-78
Ghiasi, Homayon; Osorio, Yanira; Hedvat, Yahya et al. (2002) Infection of BALB/c mice with a herpes simplex virus type 1 recombinant virus expressing IFN-gamma driven by the LAT promoter. Virology 302:144-54
Ghiasi, H; Cai, S; Perng, G C et al. (2000) The role of natural killer cells in protection of mice against death and corneal scarring following ocular HSV-1 infection. Antiviral Res 45:33-45
Ghiasi, H; Perng, G C; Nesburn, A B et al. (2000) Antibody-dependent enhancement of HSV-1 infection by anti-gK sera. Virus Res 68:137-44
Ghiasi, H; Hofman, F M; Wallner, K et al. (2000) Corneal macrophage infiltrates following ocular herpes simplex virus type 1 challenge vary in BALB/c mice vaccinated with different vaccines. Vaccine 19:1266-73
Ghiasi, H; Cai, S; Perng, G C et al. (2000) Both CD4+ and CD8+ T cells are involved in protection against HSV-1 induced corneal scarring. Br J Ophthalmol 84:408-12
Ghiasi, H; Perng, G C; Hofman, F M et al. (1999) Specific and nonspecific immune stimulation of MHC-II-deficient mice results in chronic HSV-1 infection of the trigeminal ganglia following ocular challenge. Virology 258:208-16
Ghiasi, H; Cai, S; Perng, G et al. (1999) Perforin pathway is essential for protection of mice against lethal ocular HSV-1 challenge but not corneal scarring. Virus Res 65:97-101
Ghiasi, H; Hofman, F M; Cai, S et al. (1999) Vaccination with different HSV-1 glycoproteins induces different patterns of ocular cytokine responses following HSV-1 challenge of vaccinated mice. Vaccine 17:2576-82
Ghiasi, H; Cai, S; Slanina, S M et al. (1999) The role of interleukin (IL)-2 and IL-4 in herpes simplex virus type 1 ocular replication and eye disease. J Infect Dis 179:1086-93

Showing the most recent 10 out of 26 publications