Lewis, Ryan W; Hess, George P; Ganem, Bruce (2011) Use of multicomponent reactions in developing small-molecule tools to study GABAA receptor mechanism and function. Future Med Chem 3:243-50
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Ramakrishnan, Latha; Hess, George P (2010) Mechanism of potentiation of a dysfunctional epilepsy-linked mutated GABA(A) receptor by a neurosteroid (3alpha, 21-dihydroxy-5alpha-pregnan-20-one): transient kinetic investigations. Biochemistry 49:7892-901
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Fan, Lijun; Lewis, Ryan W; Hess, George P et al. (2009) A new synthesis of caged GABA compounds for studying GABAA receptors. Bioorg Med Chem Lett 19:3932-3
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Shembekar, Vishakha R; Chen, Yongli; Carpenter, Barry K et al. (2007) Coumarin-caged glycine that can be photolyzed within 3 microseconds by visible light. Biochemistry 46:5479-84
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Krivoshein, Arcadius V; Hess, George P (2006) On the mechanism of alleviation by phenobarbital of the malfunction of an epilepsy-linked GABA(A) receptor. Biochemistry 45:11632-41
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Shembekar, Vishakha R; Chen, Yongli; Carpenter, Barry K et al. (2005) A protecting group for carboxylic acids that can be photolyzed by visible light. Biochemistry 44:7107-14
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Ramakrishnan, Latha; Hess, George P (2004) On the mechanism of a mutated and abnormally functioning gamma-aminobutyric acid (A) receptor linked to epilepsy. Biochemistry 43:7534-40
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Wieboldt, Raymond; Ramesh, Doraiswamy; Jabri, Evelyn et al. (2002) Synthesis and characterization of photolabile o-nitrobenzyl derivatives of urea. J Org Chem 67:8827-31
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Breitinger, H G; Geetha, N; Hess, G P (2001) Inhibition of the serotonin 5-HT3 receptor by nicotine, cocaine, and fluoxetine investigated by rapid chemical kinetic techniques. Biochemistry 40:8419-29
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Xia, Q; Ganem, B (2001) Asymmetric total synthesis of (-)-alpha-kainic acid using an enantioselective, metal-promoted ene cyclization. Org Lett 3:485-7
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