This research proposal describes a program directed towards the total synthesis of two complex macrolide natural products: nystatin and halichondrin B. These compounds exhibit potent antifungal (nystatin) and antitumor activities (nystatin and halichondrin B).

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM026879-12
Application #
3274342
Study Section
Medicinal Chemistry Study Section (MCHA)
Project Start
1990-04-01
Project End
1993-03-31
Budget Start
1991-04-01
Budget End
1992-03-31
Support Year
12
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Type
Schools of Arts and Sciences
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093