Over the last 20 years, important advances have been made in understanding the problem of venous thromboembolism. Predisposing factors are better understood, effective methods of prophylaxis are available, reliable diagnostic tests have been developed, and effective treatment for deep venous thrombosis (DVT) is available. The new effect of these recent advances should be to greatly decrease morbitity and mortality from venous thromboembolism, resulting in significant cost-savings; however, pulmonary embolism (PE) still causes an estimated 100,000 to 200,00 deaths each year. Little data exist documenting the current patterns of practice in the management of DVT/PE, and it remains unclear why so many patients continue to die from a largely preventable disease. The proposed investigation will attempt to answer this question through a community-wide study of the clinical factors, management criteria, and approaches used by an estimated 750 physicians practicing in 17 Metropolitan Worcester hospitals in their diagnosis and treatment of deep venous thrombosis and pulmonary embolism. These data will be used to identify problems in current patterns of clinical practice. An educational program will then be conducted in a randomized controlled design format to correct identified deficiencies. The effect of this educational program on selected clinical outcomes and cost-savings will be subsequently examined. These results will provide objective data to document current practices and to establish the value of specific educational interventions in improving the management of DVT/PE.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL035862-03
Application #
3350245
Study Section
(SRC)
Project Start
1986-04-01
Project End
1991-03-31
Budget Start
1988-04-01
Budget End
1989-03-31
Support Year
3
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of Massachusetts Medical School Worcester
Department
Type
Schools of Medicine
DUNS #
660735098
City
Worcester
State
MA
Country
United States
Zip Code
01655
Huang, Wei; Goldberg, Robert J; Anderson, Frederick A et al. (2014) Secular trends in occurrence of acute venous thromboembolism: the Worcester VTE study (1985-2009). Am J Med 127:829-39.e5
Anderson Jr, F A; Wheeler, H B; Goldberg, R J et al. (1994) Changing clinical practice. Prospective study of the impact of continuing medical education and quality assurance programs on use of prophylaxis for venous thromboembolism. Arch Intern Med 154:669-77
Anderson Jr, F A; Wheeler, H B (1992) Physician practices in the management of venous thromboembolism: a community-wide survey. J Vasc Surg 16:707-14
Anderson Jr, F A; Wheeler, H B; Goldberg, R J et al. (1992) The prevalence of risk factors for venous thromboembolism among hospital patients. Arch Intern Med 152:1660-4
Anderson Jr, F A; Wheeler, H B; Goldberg, R J et al. (1991) Physician practices in the prevention of venous thromboembolism. Ann Intern Med 115:591-5
Wheeler, H B; Anderson Jr, F A (1991) Prophylaxis against venous thromboembolism in surgical patients. Am J Surg 161:507-11
Anderson Jr, F A; Wheeler, H B; Goldberg, R J et al. (1991) A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT Study. Arch Intern Med 151:933-8