Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL051456-03
Application #
2029025
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1994-09-30
Project End
1997-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02215
Avraham, Hava; Avraham, Shalom; Zagozdzon, Radoslaw (2004) Use of antisense oligonucleotide technology to investigate signaling pathways in megakaryocytes. Methods Mol Biol 273:397-406
Lee, Byeong-Chel; Cha, Kiweon; Avraham, Shalom et al. (2004) Microarray analysis of differentially expressed genes associated with human ovarian cancer. Int J Oncol 24:847-51
Avraham, Hava Karsenty; Lee, Tae-Hee; Koh, Youngho et al. (2003) Vascular endothelial growth factor regulates focal adhesion assembly in human brain microvascular endothelial cells through activation of the focal adhesion kinase and related adhesion focal tyrosine kinase. J Biol Chem 278:36661-8
Li, Huchun; Lee, Tae-Hee; Avraham, Hava (2002) A novel tricomplex of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer. J Biol Chem 277:20965-73
Zagozdzon, Radoslaw; Bougeret, Cecile; Fu, Yigong et al. (2002) Overexpression of the Csk homologous kinase facilitates phosphorylation of Akt/PKB in MCF-7 cells. Int J Oncol 21:1347-52
McShan, Gina D; Zagozdzon, Radoslaw; Park, Shin-Young et al. (2002) Csk homologous kinase associates with RAFTK/Pyk2 in breast cancer cells and negatively regulates its activation and breast cancer cell migration. Int J Oncol 21:197-205
Lee, Tae-Hee; Avraham, Hava; Lee, Seung-Hoon et al. (2002) Vascular endothelial growth factor modulates neutrophil transendothelial migration via up-regulation of interleukin-8 in human brain microvascular endothelial cells. J Biol Chem 277:10445-51
Zhang, X F; Wang, J F; Matczak, E et al. (2001) Janus kinase 2 is involved in stromal cell-derived factor-1alpha-induced tyrosine phosphorylation of focal adhesion proteins and migration of hematopoietic progenitor cells. Blood 97:3342-8
Avraham, H; Park, S Y; Schinkmann, K et al. (2000) RAFTK/Pyk2-mediated cellular signalling. Cell Signal 12:123-33
Radisavljevic, Z; Avraham, H; Avraham, S (2000) Vascular endothelial growth factor up-regulates ICAM-1 expression via the phosphatidylinositol 3 OH-kinase/AKT/Nitric oxide pathway and modulates migration of brain microvascular endothelial cells. J Biol Chem 275:20770-4

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