The investigators propose to expand upon a preliminary finding that one or more regions of classic auditory association cortex posterior to A1 are sites of multisensory convergence, in that they respond to somatosensory stimuli, as well as sounds. This surprising finding disputes a prevailing view that multisensory integration is confined to specialized, higher order """"""""association"""""""" structures. It also bears on the fundamental question of whether auditory and somatosensory systems have """"""""what"""""""" and """"""""where"""""""" divisions like those proposed for the visual pathways. Anatomical tracer studies, in conjunction with standard multiunit / single unit mapping procedures in anesthetized monkeys and with multielectrode studies in awake monkeys will address 3 specific aims. 1) To delineate the somatosensory map(s) and determine of the relationship of somatosensory representation to previously defined auditory fields. 2) To identify the anatomical source(s) of somatosensory input. 3) To determine the functional significance of auditory-somatosensory co-representation. These experiments will evaluate the hypotheses that the caudal belt and parabelt regions of auditory cortex are involved in auditory localization and that somatosensory-auditory interactions contribute to this function.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH061989-02
Application #
6392845
Study Section
Special Emphasis Panel (ZRG1-IFCN-5 (01))
Project Start
2000-07-10
Project End
2005-06-30
Budget Start
2001-07-01
Budget End
2002-06-30
Support Year
2
Fiscal Year
2001
Total Cost
$204,051
Indirect Cost
Name
Nathan Kline Institute for Psychiatric Research
Department
Type
DUNS #
167204762
City
Orangeburg
State
NY
Country
United States
Zip Code
10962
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