Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS022571-09
Application #
2264550
Study Section
Special Emphasis Panel (ZRG1-NEUB-2 (01))
Project Start
1987-07-01
Project End
1998-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Surgery
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Ferimer, H N; Kutina, K L; LaManna, J C (1995) Methyl isobutyl amiloride delays normalization of brain intracellular pH after cardiac arrest in rats. Crit Care Med 23:1106-11
Yao, H; Ginsberg, M D; Eveleth, D D et al. (1995) Local cerebral glucose utilization and cytoskeletal proteolysis as indices of evolving focal ischemic injury in core and penumbra. J Cereb Blood Flow Metab 15:398-408
LaManna, J C; Griffith, J K; Cordisco, B R et al. (1995) Rapid recovery of rat brain intracellular pH after cardiac arrest and resuscitation. Brain Res 687:175-81
Hoffman, T L; LaManna, J C; Pundik, S et al. (1994) Early reversal of acidosis and metabolic recovery following ischemia. J Neurosurg 81:567-73
LaManna, J C; Harrington, J F; Vendel, L M et al. (1993) Regional blood-brain lactate influx. Brain Res 614:164-70
Griffith, J K; Cordisco, B R; Lin, C W et al. (1992) Distribution of intracellular pH in the rat brain cortex after global ischemia as measured by color film histophotometry of neutral red. Brain Res 573:1-7
Crumrine, R C; Selman, W R; LaManna, J C et al. (1992) Protein kinase C activity in permanent focal cerebral ischemia. Mol Chem Neuropathol 16:85-93
LaManna, J C; Griffith, J K; Cordisco, B R et al. (1992) Intracellular pH in rat brain in vivo and in brain slices. Can J Physiol Pharmacol 70 Suppl:S269-77
Crumrine, R C; LaManna, J C; Lust, W D (1991) Regional changes in intracellular pH determined by neutral red histophotometry and high energy metabolites during cardiac arrest and following resuscitation in the rat. Metab Brain Dis 6:145-55
Selman, W R; Ricci, A J; Crumrine, R C et al. (1990) The evolution of focal ischemic damage: a metabolic analysis. Metab Brain Dis 5:33-44

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