Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Exploratory/Developmental Grants (R21)
Project #
5R21CA069773-02
Application #
2009350
Study Section
Special Emphasis Panel (SRC (06))
Project Start
1995-09-30
Project End
1999-08-31
Budget Start
1996-09-12
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Duke University
Department
Surgery
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Gilbert, Jill; Rudek, Michelle A; Higgins, Michaela J et al. (2012) A phase I trial of erlotinib and concurrent chemoradiotherapy for stage III and IV (M0) squamous cell carcinoma of the head and neck. Clin Cancer Res 18:1735-42
Ray, Balmiki; Bisht, Savita; Maitra, Amarnath et al. (2011) Neuroprotective and neurorescue effects of a novel polymeric nanoparticle formulation of curcumin (NanoCurcâ„¢) in the neuronal cell culture and animal model: implications for Alzheimer's disease. J Alzheimers Dis 23:61-77
Weekes, Colin D; Nallapareddy, Sujatha; Rudek, Michelle A et al. (2011) Thymidylate synthase (TYMS) enhancer region genotype-directed phase II trial of oral capecitabine for 2nd line treatment of advanced pancreatic cancer. Invest New Drugs 29:1057-65
Fracasso, Paula M; Williams, Kerry J; Chen, Ronald C et al. (2011) A Phase 1 study of UCN-01 in combination with irinotecan in patients with resistant solid tumor malignancies. Cancer Chemother Pharmacol 67:1225-37
Karp, Judith E; Smith, B Douglas; Resar, Linda S et al. (2011) Phase 1 and pharmacokinetic study of bolus-infusion flavopiridol followed by cytosine arabinoside and mitoxantrone for acute leukemias. Blood 117:3302-10
Smith, B Douglas; Jones, Richard J; Cho, Eunpi et al. (2011) Differentiation therapy in poor risk myeloid malignancies: Results of a dose finding study of the combination bryostatin-1 and GM-CSF. Leuk Res 35:87-94
Stearns, Vered; Mori, Tsuyoshi; Jacobs, Lisa K et al. (2011) Preclinical and clinical evaluation of intraductally administered agents in early breast cancer. Sci Transl Med 3:106ra108
Bisht, Savita; Khan, Mehtab A; Bekhit, Mena et al. (2011) A polymeric nanoparticle formulation of curcumin (NanoCurcâ„¢) ameliorates CCl4-induced hepatic injury and fibrosis through reduction of pro-inflammatory cytokines and stellate cell activation. Lab Invest 91:1383-95
Connolly, Roisin M; Rudek, Michelle A; Garrett-Mayer, Elizabeth et al. (2011) Docetaxel metabolism is not altered by imatinib: findings from an early phase study in metastatic breast cancer. Breast Cancer Res Treat 127:153-62
Armstrong, Andrew J; Netto, George J; Rudek, Michelle A et al. (2010) A pharmacodynamic study of rapamycin in men with intermediate- to high-risk localized prostate cancer. Clin Cancer Res 16:3057-66

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