Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37DE006746-20
Application #
6696775
Study Section
Special Emphasis Panel (NSS)
Program Officer
Lunsford, Dwayne
Project Start
1984-01-01
Project End
2008-12-31
Budget Start
2004-01-23
Budget End
2004-12-31
Support Year
20
Fiscal Year
2004
Total Cost
$276,932
Indirect Cost

  Institution

Name
State University of New York at Buffalo
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
038633251
City
Buffalo
State
NY
Country
United States
Zip Code
14260

  Publications

Zhao, W; Zhao, Z; Russell, M W (2011) Characterization of antigen-presenting cells induced by intragastric immunization with recombinant chimeric immunogens constructed from Streptococcus mutans AgI/II and type I or type II heat-labile enterotoxins. Mol Oral Microbiol 26:200-9
Russell, Michael W; Mestecky, Jiri (2010) Tolerance and protection against infection in the genital tract. Immunol Invest 39:500-25
Mestecky, Jiri; Russell, Michael W (2009) Specific antibody activity, glycan heterogeneity and polyreactivity contribute to the protective activity of S-IgA at mucosal surfaces. Immunol Lett 124:57-62
Liang, Shuang; Hosur, Kavita B; Nawar, Hesham F et al. (2009) In vivo and in vitro adjuvant activities of the B subunit of Type IIb heat-labile enterotoxin (LT-IIb-B5) from Escherichia coli. Vaccine 27:4302-8
Ostberg, K L; Russell, M W; Murphy, T F (2009) Mucosal immunization of mice with recombinant OMP P2 induces antibodies that bind to surface epitopes of multiple strains of nontypeable Haemophilus influenzae. Mucosal Immunol 2:63-73
Mestecky, Jiri; Russell, Michael W; Elson, Charles O (2007) Perspectives on mucosal vaccines: is mucosal tolerance a barrier? J Immunol 179:5633-8
Nawar, Hesham F; Arce, Sergio; Russell, Michael W et al. (2007) Mutants of type II heat-labile enterotoxin LT-IIa with altered ganglioside-binding activities and diminished toxicity are potent mucosal adjuvants. Infect Immun 75:621-33
Liang, Shuang; Wang, Min; Triantafilou, Kathy et al. (2007) The A subunit of type IIb enterotoxin (LT-IIb) suppresses the proinflammatory potential of the B subunit and its ability to recruit and interact with TLR2. J Immunol 178:4811-9
Arce, Sergio; Nawar, Hesham F; Muehlinghaus, Gwendolin et al. (2007) In vitro induction of immunoglobulin A (IgA)- and IgM-secreting plasma blasts by cholera toxin depends on T-cell help and is mediated by CD154 up-regulation and inhibition of gamma interferon synthesis. Infect Immun 75:1413-23
Nawar, Hesham F; Arce, Sergio; Russell, Michael W et al. (2005) Mucosal adjuvant properties of mutant LT-IIa and LT-IIb enterotoxins that exhibit altered ganglioside-binding activities. Infect Immun 73:1330-42

Showing the most recent 10 out of 70 publications