Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37MH016841-29
Application #
2243345
Study Section
Special Emphasis Panel (NSS)
Project Start
1988-09-01
Project End
1998-05-31
Budget Start
1996-09-01
Budget End
1997-05-31
Support Year
29
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Allegheny University of Health Sciences
Department
Pharmacology
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19129
Schindler, Emmanuelle A D; Harvey, John A; Aloyo, Vincent J (2013) Phospholipase C mediates (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-, but not lysergic acid diethylamide (LSD)-elicited head bobs in rabbit medial prefrontal cortex. Brain Res 1491:98-108
Schindler, Emmanuelle A D; Dave, Kuldip D; Smolock, Elaine M et al. (2012) Serotonergic and dopaminergic distinctions in the behavioral pharmacology of (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Pharmacol Biochem Behav 101:69-76
Scarlota, Laura C; Harvey, John A; Aloyo, Vincent J (2011) The role of serotonin-2 (5-HT2) and dopamine receptors in the behavioral actions of the 5-HT2A/2C agonist, DOI, and putative 5-HT2C inverse agonist, SR46349B. Psychopharmacology (Berl) 213:393-401
Romano, Anthony G; Quinn, Jennifer L; Li, Luchuan et al. (2010) Intrahippocampal LSD accelerates learning and desensitizes the 5-HT(2A) receptor in the rabbit, Romano et al. Psychopharmacology (Berl) 212:441-8
Oristaglio, Jeff; Romano, Anthony G; Harvey, John A (2009) Amphetamine influences conditioned response timing and laterality of anterior cingulate cortex activity during rabbit delay eyeblink conditioning. Neurobiol Learn Mem 92:1-18
Aloyo, V J; Berg, K A; Spampinato, U et al. (2009) Current status of inverse agonism at serotonin2A (5-HT2A) and 5-HT2C receptors. Pharmacol Ther 121:160-73
Romano, A G; Du, W; Harvey, J A (1994) Methylenedioxyamphetamine: a selective effect on cortical content and turnover of 5-HT. Pharmacol Biochem Behav 49:599-607
Chen, J F; Aloyo, V J; Qin, Z H et al. (1994) Irreversible blockade of D2 dopamine receptors by fluphenazine-N-mustard increases D2 dopamine receptor mRNA and proenkephalin mRNA and decreases D1 dopamine receptor mRNA and mu and delta opioid receptors in rat striatum. Neurochem Int 25:355-66
Chen, J F; Aloyo, V J; Weiss, B (1993) Continuous treatment with the D2 dopamine receptor agonist quinpirole decreases D2 dopamine receptors, D2 dopamine receptor messenger RNA and proenkephalin messenger RNA, and increases mu opioid receptors in mouse striatum. Neuroscience 54:669-80
Harvey, J A; Welsh, J P; Yeo, C H et al. (1993) Recoverable and nonrecoverable deficits in conditioned responses after cerebellar cortical lesions. J Neurosci 13:1624-35

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