Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
1R37MH045923-01
Application #
3486972
Study Section
Neurosciences Research Review Committee (BPN)
Project Start
1990-03-01
Project End
1992-12-31
Budget Start
1990-03-01
Budget End
1990-12-31
Support Year
1
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Type
Schools of Medicine
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10027
Jin, Iksung; Puthanveettil, Sathya; Udo, Hiroshi et al. (2012) Spontaneous transmitter release is critical for the induction of long-term and intermediate-term facilitation in Aplysia. Proc Natl Acad Sci U S A 109:9131-6
Jin, Iksung; Udo, Hiroshi; Rayman, Joseph B et al. (2012) Spontaneous transmitter release recruits postsynaptic mechanisms of long-term and intermediate-term facilitation in Aplysia. Proc Natl Acad Sci U S A 109:9137-42
Jin, Iksung; Udo, Hiroshi; Hawkins, Robert D (2011) Rapid increase in clusters of synaptophysin at onset of homosynaptic potentiation in Aplysia. Proc Natl Acad Sci U S A 108:11656-61
Jin, Iksung; Kandel, Eric R; Hawkins, Robert D (2011) Whereas short-term facilitation is presynaptic, intermediate-term facilitation involves both presynaptic and postsynaptic protein kinases and protein synthesis. Learn Mem 18:96-102
DeCostanzo, Anthony J; Voloshyna, Iryna; Rosen, Zev B et al. (2010) 12-Lipoxygenase regulates hippocampal long-term potentiation by modulating L-type Ca2+ channels. J Neurosci 30:1822-31
Nolan, Matthew F; Malleret, Gael; Dudman, Josh T et al. (2004) A behavioral role for dendritic integration: HCN1 channels constrain spatial memory and plasticity at inputs to distal dendrites of CA1 pyramidal neurons. Cell 119:719-32
Nolan, Matthew F; Malleret, Gael; Lee, Ka Hung et al. (2003) The hyperpolarization-activated HCN1 channel is important for motor learning and neuronal integration by cerebellar Purkinje cells. Cell 115:551-64
Bartsch, D; Casadio, A; Karl, K A et al. (1998) CREB1 encodes a nuclear activator, a repressor, and a cytoplasmic modulator that form a regulatory unit critical for long-term facilitation. Cell 95:211-23
Nguyen, P V; Kandel, E R (1997) Brief theta-burst stimulation induces a transcription-dependent late phase of LTP requiring cAMP in area CA1 of the mouse hippocampus. Learn Mem 4:230-43
Skehel, P A; Martin, K C; Kandel, E R et al. (1995) A VAMP-binding protein from Aplysia required for neurotransmitter release. Science 269:1580-3

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