This proposal presents a plan to design and produce a software product for DNA fragment assembly that meets the needs of large-scale sequencing efforts. The effort demands software that is fast and highly accurate. DNASTAR?s proposed product will meet the needs through the development of new fragment assembly software that incorporates a novel linear-time algorithm extended to handle myriad fragment reads; a highly accurate consensus-caller; efficient methods for handling repeats; access to databases; full use of fragment reads; base call quality scores; and physical map constraints. The combination will form a unique package of the fastest, most accurate, and most flexible software available for DNA sequencing.

Proposed Commercial Applications

Not Available

Agency
National Institute of Health (NIH)
Institute
National Human Genome Research Institute (NHGRI)
Type
Small Business Innovation Research Grants (SBIR) - Phase II (R44)
Project #
2R44HG001893-02A1
Application #
6312112
Study Section
Special Emphasis Panel (ZRG1-SSS-Y (01))
Program Officer
Felsenfeld, Adam
Project Start
1999-01-01
Project End
2002-12-31
Budget Start
2000-01-01
Budget End
2001-12-31
Support Year
2
Fiscal Year
2001
Total Cost
$472,455
Indirect Cost
Name
Dnastar, Inc.
Department
Type
DUNS #
130194947
City
Madison
State
WI
Country
United States
Zip Code
53705