This competing-continuation T32 application (Advanced Training in Oral Biology) requests funding to support the research career development of eligible applicants who wish to pursue careers as independent investigators and leaders in dental, oral, and craniofacial health research. Trainees of our long-established program are encouraged to follow their interests to become prepared to lead a research program involving basic, translational and/or clinical research, participate as expert investigators in multidisciplinary team science projects, and provide leadership in biomedical science research. The major research areas encompassed by the program include microbiology, salivary research, genomics-glycomics-microbiome studies, craniofacial and tooth development, hard-tissue biology, host defense, and periodontal research. The proposed duration of the training leading to completion of the PhD degree is 4 years. For post-doctoral training, 3 years are proposed. The Ph.D. and post-doctoral training programs in the Department of Oral Biology at the University at Buffalo (UB) School of Dental Medicine have to date supported 90 individuals who have earned their Ph.D. degree in Oral Biology, and a large number of post-doctoral fellows, most of whom entered the faculties of numerous dental schools, research institutes, and industry research programs throughout the world. The Training Faculty includes a diverse mix of 23 investigators who lead productive research programs with substantial experience in training pre-doctoral and postdoctoral fellows. Trainees will benefit from many available resources and learning opportunities, including a strong didactic curriculum, journal clubs and seminars, access to basic science and clinical research core facilities, and career development activities. After successfully completing their training, we anticipate our trainees to have reached a level of experience in experimental techniques, scientific thinking, and academic skills that will enable them to pursue successful careers as independent scientists in research, industry, and clinic.
The Advanced Training in Oral Biology program at the School of Dental Medicine at the University at Buffalo offers a wide range of research-intensive interdisciplinary graduate and post-doctoral programs to train the next generation of oral health biomedical scientists. The goal of the program is to attract pre-doctoral and post- doctoral trainees into oral biology research careers. This proposal requests continuation of support for both our Ph.D. program to train dentists (post-D.D.S.) and non-dentists (pre-doctoral), and for our post-doctoral program to train post-doctoral fellows.
|Ruscitto, A; Sharma, A (2018) Peptidoglycan synthesis in Tannerella forsythia: Scavenging is the modus operandi. Mol Oral Microbiol 33:125-132|
|Min, Sangwon; Song, Eun-Ah Christine; Oyelakin, Akinsola et al. (2018) Functional characterization and genomic studies of a novel murine submandibular gland epithelial cell line. PLoS One 13:e0192775|
|Settem, R P; Honma, K; Shankar, M et al. (2018) Tannerella forsythia-produced methylglyoxal causes accumulation of advanced glycation endproducts to trigger cytokine secretion in human monocytes. Mol Oral Microbiol 33:292-299|
|Norris, Hannah L; Friedman, Justin; Chen, Ziqiang et al. (2018) Salivary metals, age, and gender correlate with cultivable oral Candida carriage levels. J Oral Microbiol 10:1447216|
|Cross, Benjamin W; Ruhl, Stefan (2018) Glycan recognition at the saliva - oral microbiome interface. Cell Immunol 333:19-33|
|Jephthah, Stephanie; Henriques, João; Cragnell, Carolina et al. (2017) Structural Characterization of Histatin 5-Spermidine Conjugates: A Combined Experimental and Theoretical Study. J Chem Inf Model 57:1330-1341|
|Chinthamani, Sreedevi; Settem, Rajendra P; Honma, Kiyonobu et al. (2017) Macrophage inducible C-type lectin (Mincle) recognizes glycosylated surface (S)-layer of the periodontal pathogen Tannerella forsythia. PLoS One 12:e0173394|
|Kiripolsky, Jeremy; Shen, Long; Liang, Yichen et al. (2017) Systemic manifestations of primary Sjögren's syndrome in the NOD.B10Sn-H2b/J mouse model. Clin Immunol 183:225-232|
|Varanat, M; Haase, E M; Kay, J G et al. (2017) Activation of the TREM-1 pathway in human monocytes by periodontal pathogens and oral commensal bacteria. Mol Oral Microbiol 32:275-287|
|Aljanobi, Hawra; Sabharwal, Amarpreet; Krishnakumar, Bralavan et al. (2017) Is it Sjögren's syndrome or burning mouth syndrome? Distinct pathoses with similar oral symptoms. Oral Surg Oral Med Oral Pathol Oral Radiol 123:482-495|
Showing the most recent 10 out of 46 publications