Abstract

This project is in an intense data analysis phase with several papers published, in press, or under preparation. Plans to follow up primarily phenotype analyses with genetic analyses are under development. In addition, preliminary plans to follow-up this cohort in 2010 are under consideration and behind the scenes work to implement this is happening.? ? The MESA Study has several ancillary studies one of which is this ocular component. Others include a lung component, and an air pollution component. Discussions to integrate and analyze data across components have resulted in several paper proposals. More information about the MESA Study, including a full list of participating investigators and institutions, can be found at www.mesa-nhlbi.org.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Intramural Research (Z01)
Project #
1Z01EY000403-06
Application #
7594079
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
6
Fiscal Year
2007
Total Cost
$43,269
Indirect Cost

  Institution

Name
U.S. National Eye Institute
Department
Type
DUNS #
City
State
Country
United States
Zip Code

  Publications

Liang, Dongchun; Zuo, Aijun; Shao, Hui et al. (2013) Retinoic acid inhibits CD25+ dendritic cell expansion and ?? T-cell activation in experimental autoimmune uveitis. Invest Ophthalmol Vis Sci 54:3493-503
Yau, Joanne Wen Yee; Xie, Jing; Lamoureux, Ecosse et al. (2012) Retinal microvascular calibre and risk of incident diabetes: the multi-ethnic study of atherosclerosis. Diabetes Res Clin Pract 95:265-74
Greenstein, Max B; Myers, Chelsea E; Meuer, Stacy M et al. (2011) Prevalence and characteristics of choroidal nevi: the multi-ethnic study of atherosclerosis. Ophthalmology 118:2468-73
Kawasaki, Ryo; Cheung, Ning; Islam, F M Amirul et al. (2011) Is diabetic retinopathy related to subclinical cardiovascular disease? Ophthalmology 118:860-5
Yau, Joanne Wen Yee; Xie, Jing; Kawasaki, Ryo et al. (2011) Retinal arteriolar narrowing and subsequent development of CKD Stage 3: the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Kidney Dis 58:39-46
Ng, Ching Hui; Cheung, Ning; Wang, Jie Jin et al. (2011) Prevalence and risk factors for epiretinal membranes in a multi-ethnic United States population. Ophthalmology 118:694-9
Adar, Sara D; Klein, Ronald; Klein, Barbara E K et al. (2010) Air Pollution and the microvasculature: a cross-sectional assessment of in vivo retinal images in the population-based multi-ethnic study of atherosclerosis (MESA). PLoS Med 7:e1000372
Nguyen, Thanh T; Islam, F M Amirul; Farouque, H M Omar et al. (2010) Retinal vascular caliber and brachial flow-mediated dilation: the Multi-Ethnic Study of Atherosclerosis. Stroke 41:1343-8
Jensen, Richard A; Shea, Steven; Ranjit, Nalini et al. (2010) Psychosocial risk factors and retinal microvascular signs: the multi-ethnic study of atherosclerosis. Am J Epidemiol 171:522-31
Kreis, Andreas J; Wong, Tien Yin; Islam, F M Amirul et al. (2009) Is nuclear magnetic resonance lipoprotein subclass related to diabetic retinopathy? The multi-ethnic study of atherosclerosis (MESA). Diab Vasc Dis Res 6:40-2

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