Abstract

This project remains in an intense data analysis phase. Several papers involving ocular topics have been published, are in press, or are under preparation. Work to follow up primarily phenotype analyses with genetic analyses is also on-going. ? ? Plans to re-examine this cohort in 2010 have been developed, reviewed, and funded. Preparatory work to implement this follow-up examination is underway.? ? The MESA Study has several ancillary studies one of which is this ocular component. Others ancillary studies to MESA include a lung component (funded by NHLBI) and an air pollution component (funded by the EPA). Discussions to integrate and analyze data across various study components have resulted in several paper proposals with manuscripts in process. ? ? More information about the MESA Study, including a full list of participating investigators and institutions and a complete list of publications to-date, can be found at www.mesa-nhlbi.org.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Intramural Research (Z01)
Project #
1Z01EY000403-07
Application #
7734622
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
7
Fiscal Year
2008
Total Cost
$106,276
Indirect Cost

  Institution

Name
U.S. National Eye Institute
Department
Type
DUNS #
City
State
Country
United States
Zip Code

  Publications

Liang, Dongchun; Zuo, Aijun; Shao, Hui et al. (2013) Retinoic acid inhibits CD25+ dendritic cell expansion and ?? T-cell activation in experimental autoimmune uveitis. Invest Ophthalmol Vis Sci 54:3493-503
Yau, Joanne Wen Yee; Xie, Jing; Lamoureux, Ecosse et al. (2012) Retinal microvascular calibre and risk of incident diabetes: the multi-ethnic study of atherosclerosis. Diabetes Res Clin Pract 95:265-74
Greenstein, Max B; Myers, Chelsea E; Meuer, Stacy M et al. (2011) Prevalence and characteristics of choroidal nevi: the multi-ethnic study of atherosclerosis. Ophthalmology 118:2468-73
Kawasaki, Ryo; Cheung, Ning; Islam, F M Amirul et al. (2011) Is diabetic retinopathy related to subclinical cardiovascular disease? Ophthalmology 118:860-5
Yau, Joanne Wen Yee; Xie, Jing; Kawasaki, Ryo et al. (2011) Retinal arteriolar narrowing and subsequent development of CKD Stage 3: the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Kidney Dis 58:39-46
Ng, Ching Hui; Cheung, Ning; Wang, Jie Jin et al. (2011) Prevalence and risk factors for epiretinal membranes in a multi-ethnic United States population. Ophthalmology 118:694-9
Adar, Sara D; Klein, Ronald; Klein, Barbara E K et al. (2010) Air Pollution and the microvasculature: a cross-sectional assessment of in vivo retinal images in the population-based multi-ethnic study of atherosclerosis (MESA). PLoS Med 7:e1000372
Nguyen, Thanh T; Islam, F M Amirul; Farouque, H M Omar et al. (2010) Retinal vascular caliber and brachial flow-mediated dilation: the Multi-Ethnic Study of Atherosclerosis. Stroke 41:1343-8
Jensen, Richard A; Shea, Steven; Ranjit, Nalini et al. (2010) Psychosocial risk factors and retinal microvascular signs: the multi-ethnic study of atherosclerosis. Am J Epidemiol 171:522-31
Kreis, Andreas J; Wong, Tien Yin; Islam, F M Amirul et al. (2009) Is nuclear magnetic resonance lipoprotein subclass related to diabetic retinopathy? The multi-ethnic study of atherosclerosis (MESA). Diab Vasc Dis Res 6:40-2

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