Abstract

The compartive metabolism of o-toluidine in the rat, hamster and guinea pig begun in the preceding grant period will be continued and expanded to include p-toluidine. Emphasis will be placed on evaluating differences in the N-oxidation of the arylamines in these species. 14C-labeled (ring) ortho and para anisidines will be synthesized and their metabolism in the rat will be determined.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES003432-06
Application #
3250701
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Project Start
1979-07-01
Project End
1987-02-28
Budget Start
1986-03-01
Budget End
1987-02-28
Support Year
6
Fiscal Year
1986
Total Cost
Indirect Cost

  Institution

Name
Institute for Cancer Prevention
Department
Type
DUNS #
City
Valhalla
State
NY
Country
United States
Zip Code
10595